Biomedical papers, 2022 (vol. 166), issue 4 #adessonewsitalia
Tumour volume and radiotherapy prolongation in locally advanced head and neck cancer patients treated with radical IMRT
Radka Lohynska, Michaela Jirkovska, Bela Malinova, Alena Novakova-Jiresova, Zdenka Pechacova, Zuzana Kratka
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2022, 166(4):405-411 | DOI: 10.5507/bp.2021.047
Factors influencing overall survival, disease-free survival, and local control in patients with locally advanced head and neck cancer after radical radioherapy were retrospectively evaluated in this paper. The most important prognostic factors were total tumor volume (GTV) and radiotherapy treatment time (RTT). The best results were achieved in patients with GTV ≤ 55 cc and RTT ≤ 48 days (mean LC 8.1, DFS 7.1 and OS 6.4 years) and the worst results with GTV > 55 cc and RTT > 48 days (mean LC 4.4, mean DFS 3.2 and median OS 2.6 years).
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